20 October 2008
Automated transgenic sorters?
Fluorescence activated cell sorters (FACs) are well-established machines able to separate different cell populations on the basis of their inner fluorescence. Although technical challenging, new strategies strive to adopt FACs architecture to the automated isolation of fluorescent organisms, like worms (recently appeared on Nature Methods) and Xenopus tadpoles (recently patented by WatchFrog). To date, with mice we have still to run boring PCR or setup tedious Southern blots to get out our offspring genotype. Maybe in future we will have an automated mice sorter, to date I found only an automated rodent trap patented in 1920.
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