|Bioluminescence by jon.nelson|
Of course, that is a technological advance, since it seems now possible to follow the dynamics of stem cell behavior in a manner not possible with retrospective histological analysis. We need now to develop new cognitive skills (and a little bit of statistic also) to understand this unprecedented "real time" picture, since it is quite common for generation 1.0 scientists to wonder only about "end-point" results, without considering the bulk of information revealed by longitudinally imaging in the same experimental subject.
Alessandra Sacco, Regis Doyonnas, Peggy Kraft, Stefan Vitorovic, Helen M. Blau (2008). Self-renewal and expansion of single transplanted muscle stem cells Nature DOI: 10.1038/nature07384