the system biology boundary

ResearchBlogging.orgWe have to stop to use omics technologies to turn biology (and system biology) in an exact science. Our vision of "exactiness" is inside the problem: we are organisms and our point of view, our cognitive brain, evolved together with the system we are trying to hack. We only need models in biology to getting things done, that's it. Stop packing biology in our stupid packages, let it work the model.
Fuzziness is not simply the manifestation of methodological limitations, but is also inherent in many biological problems and our reductionist approaches to them



Monika Fuxreiter, Peter Tompa (2008). Fuzzy interactome: the limitations of models in molecular biology Trends in Biochemical Sciences DOI: 10.1016/j.tibs.2008.10.006