skimming Biophotonics International

I have just received my September print copy of Biophotonics International , a monthly magazine that would collect "photonic solution f...

Blogging science to allow evidence-based decisions

Concerning research blogging, I previously wondered how it will influence research dynamics and maybe kill some boring press releases . Lit...

[movie] Dual-luciferase for membrane biogenesis

Jove is featuring a movie which explains how to study the coordination of membrane biogenesis by a...

Protein evolution switch-off fluorescent proteins (and on)

Canonical fluorescent proteins (FPs) emit light once excited by appropriate irradiation. In a peculiar group of them, the reversibly switch...

Why do you care about kinetic imaging?

A new optical imaging device has been released from Caliper, the IVIS Kinetic . Compared to older imaging workstations this new product all...

New calcium reporter for two-photon imaging in vivo

Neural networks evolve their functional features over time. At present, no techniques allow detailed neuron recording over repeated experime...

R&D efficacy revision?

An ongoing LinkedIN conversation is wondering about the steady decrease in the discovery of drugs that would eventually reach the marketpla...

surprise in my shared readings

Some months ago, I've started to share my google reader readings. Because there is a feed of it, I put it in the wordle claws. It seems ...

don't crack down bioluminescence imaging

The laboratory that discovered leptin have recently reported a BAC transgenic mouse line that express luciferase under the control of leptin...

How many building blocks do you expect in a cell?

Expectations that defined variation in the DNA blueprint would serve to pinpoint our whole inner biology was completely unfulfilled by the ...

Long introns delay transcriptional time

In a negative feedback loop, does intron lenght affects gene expression? Yan Swinburne and colleagu...

Reach Reportergene!

In this blog, I personally distill interesting biomedical news from peer-reviewed magazines and I share my thoughts with more than 25,000 sc...

Dark box? Black box?

I have been gone through a 2007 interview to Mark Roskey (vice president of reagents and applied biology at Caliper Life Sciences) appeared...

Balls electroporation?

In my humble opinion, to study functional genomics in vivo, the best would be to place your reporter gene into humanized animals (i.e. maki...

reporter gene normalization

Reporter gene normalization on google chrome browser AKA, how to warp keywords to trap new visitors...

Basal expression from inducible transgenes

Of course, a critical drawback of inducible transgene expression is the amount of basal expression (leakage) responsible to making noise in ...