A new study demonstrates the feasibility of using a lentiviral approaches to create transgenic rabbits with more efficiency than classical pronuclear injection transgenesis developed in rabbits two decades ago.
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| From: Hiripi et al., 2010 |
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Hiripi, L., Negre, D., Cosset, F., Kvell, K., Czömpöly, T., Baranyi, M., Gócza, E., Hoffmann, O., Bender, B., & Bősze, Z. (2010). Transgenic rabbit production with simian immunodeficiency virus-derived lentiviral vector Transgenic Research DOI: 10.1007/s11248-009-9356-y
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5 comments:
I'd really be curious to know how to 'opt out' of 'breakthroughs' in science that use animals as things. I don't need to live longer knowing what has been done in my name in the 'pursuit of longevity'. The world is overpopulated already. We torture animals to create humans to starve to death. I really don't get it.
I think we are progressively 'opting out' of the scientific research which exploits animals and torture them. Such a stupid research trapped us in a paradox: how to understand LIFE from DEATH samples? 200 years ago, Darwin was able to build a great scientific theory (although incomplete) just by observation of living animals in their natural enviromnent (the galapagos) without interfering. We need to know how we function at the molecular level, but the question that has challenged the human research so far is: how to do these observations at the molecular level in living animals? Reporter genes are a pragmatic solution: introducing in the animal genome a very small gene which is able to 'record' its molecular state and to 'self-report' molecular infos, without need of surgery or other invasive procedures. On 30-50,000 genes in their genome, one transgene is a 'negligible' modification (less than 0.0001%!) Definitively, implanting radio-transponders in lions or dolphins is more invasive! How to implant genes? Viruses are a natural solution: they naturally transfer genes across species. This blog strongly advocates the necessity to Revise current research, to Replace current cruel methods and to Reduce the use of animals. Reporter genes are a good compromise for such a purpose, supporting their development would eventually allow to a new awareness in biomedical research and to rescue some of the atrocities done in the past in the name of 'progress'.
Many institutions limit access to their online information. Making this information available will be an asset to all.
exactly, was that nerve? Was it the morality of genetic engineering for science, or was it more related to the fact that the rabbit was created solely for art? In addition to questioning the morality of certain aspects of science, the Alba project calls specific attention to the line between science and art. Sports Apparel
Dear juliawells, the rabbit was created merely for science.
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