Inducible cAMP early repressor splice variants ICER I and IIgamma both repress transcription of c-fos and chromogranin A

Inducible cAMP early repressor splice variants ICER I and IIgamma both repress transcription of c-fos and chromogranin A

Inducible cAMP early repressor (ICER) splice variants are generated upon activation of an alternate, intronic promoter inside the CREM gene. ICER is proposed to downregulate each its personal expression, and the expression of different genes, containing cAMP-responsive promoter parts. To look at the organic operate of the 2 ICER splice variants, I and IIgamma, in […]